Some effects of injecting a prostaglandin F2alpha (Lutalyse) during the post-partum period on the subsequent fertility of dairy cows


K.L. MacMillan, A.M. Day, V.K. Taufa, H.V. Henderson, P.A. Allison

Ruakura Animal Research Station, Ministry of Agriculture and Fisheries, Hamilton

Proceedings of the New Zealand Society of Animal Production. 1987, 47: 65-68

Three trials were completed using 1813 cows in seasonal dairy herds to study the effects of an injection of a prostaglandin F2alpha, dinoprost tromethamine (LutalyseŽ; Upjohn Co.) given from 14 to 35 d post-partum on the subsequent fertility of normally calving dairy cows (Trial 1), cows induced to calve prematurely and herdmates calving normally on similar dates (Trial 2), and all cows on a whole herd basis (Trial 3).

The prostaglandin injection did not alter interval from calving to first oestrus (48.5 d), start of the artificial breeding (AB) programme to first insemination (12.9 d), AB start to conception (24.8 d), calving to insemination (77.2 d), calving to conception (88.3 d), or the pregnancy rate to first insemination (58.5%), even though there were large differences in each of these parameters among the 5 herds in Trial 1.

The pregnancy rate to first insemination among cows induced to calve prematurely was 47.2% compared to 56.7% in normally calving herdmates with similar calving dates (Trial 2. A prostaglandin injection around 20 d post-partum did not affect this difference. In Trial 3, induced cows injected with prostaglandin from 28 to 34 d post-partum did have a higher pregnancy rate to first insemination than untreated induced herdmates (69.2% v 42.3%). None of the parameters used to measure reproductive efficiency were affected by a prostaglandin injection given from 28 to 34 d post-partum to normally calving cows in Trial 3.

The comparatively high level of fertility in the cows, combined with efficient breeding management in the herds included in these trials, may have minimised the potential usefulness of this form of prostaglandin therapy previously demonstrated in herds with less fertile cows.

Keywords: NZSAPAB; Prostaglandin; post-partum; fertility; conception; pregnancy


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Last Updated 03-05-1997