þ-lactoglobulin expression in bovine mammary tissue


C.A. Ford, M.B. Connett, R.J. Wilkins

AgResearch, Ruakura Agriculture Centre, Private Bag 3123, Hamilton, New Zealand

Proceedings of the New Zealand Society of Animal Production. 1993, 53: 167-170

The levels of the A and B variant forms of þ-lactoglobulin were measured in the milk of 70 heterozygous cows. On average, 1.2 times more A than B variant protein was found in the milk. Measurements of mRNA levels in lactating tissue from four of these animals indicated that approximately 60% more A allele than B allele mRNA was present. We conclude that differences in the two alleles, either at the level of transcription of mRNA stability, are probably responsible for the different rates of production of the corresponding protein variants.

Keywords: NZSAPAB; þ-lactoglobulin; bovine; alleles; gene expression.


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