Sequence variations in genes coding for bovine þ-lactoglobulin and
aS1-casein
R.J. Wilkins and H.W. Davey
AgResearch, Ruakura Research Centre, Hamilton, New Zealand and
Centre for Research in Animal Biology, University of Waikato, Waikato,
New Zealand.
Proceedings of the New Zealand Society of Animal Production, 1996,
56: 45-46
The techniques involved in searching for bovine milk protein variants
by the direct sequencing of genes are discussed. Examples are drawn from
our studies of two major milk protein genes, b-lactoglobulin and aS1-casein.
In the former case it was possible to subdivide the A and B variants even
further according to point mutations found in the promoter region of the
gene, while in the latter case, a New Zealand aS1 casein type A variant in
Friesians was shown to arise from a point deletion in the gene which differs
significantly from a mutation reported to give rise to the same type A
variants in the German Red breed. The potential of this analytical approach
for analysing milk protein genes is discussed.
Keywords: NZSAPAB;
bovine; milk protein variants; genes; DNA sequencing.
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Last Updated 18-03-1997
